Predicted probability was used to categorize the test as positive or negative based on a decision threshold of 0.5 (validated for identification of stage: steatosis 1, inflammation 2, ballooning 1 and fibrosis 2)
When this happens, early successes slow down, and confidence starts to fade
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Importantly, many of the pathways susceptible to redox modulation are actively involved in the pathogenesis of ALD, including the NRF2 and AMPK pathways
Rather, they are a little toxic to our cells and thus induce a hormetic response by increasing the expression of anti-oxidant genes, and this is why they are put into the category of anti-oxidants
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